Doctors Mehmet Oz and Michael Roizen (the YOU Docs) have an interesting post on the RealAge blog about why you need vacations to stay healthy. In addition to the "why" they give you some suggestions on the "hows" that can help you the most (I personally like the idea of number 3). They also have some links to some tasty foods and recipies to help you relax. This is, after all, a health blog.
If you're thinking of taking the doctors' advice and getting away for a little stress-buster time, why not hop over to AirGorilla and let a simian set you up for your vacation.